Compile Data Set for Download or QSAR
Found 90 of ic50 data for polymerid = 5581
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511484(US11059789, Example 33 | US11691950, Example 33)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511481(US11059789, Example 25 | US11691950, Example 25)copy SMILES
Affinity DataIC50: 4.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511485(US11059789, Example 27 | US11691950, Example 27)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511480(US11059789, Example 40 | US11691950, Example 40)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511483(US11059789, Example 66 | US11691950, Example 66)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM511482(US11059789, Example 83 | US11691950, Example 83)copy SMILES
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2C82FD9
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105221(US8580778, 21)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105220(US8580778, 20)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105219(US8580778, 17)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105224(US8580778, 29)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105222(US8580778, 25)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3527(US8524699, 18)copy SMILEScopy InChI
Affinity DataIC50: 180nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50042876(CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 185nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50042876(CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM109268(US8609698, 10)copy SMILEScopy InChI
Affinity DataIC50: 260nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44NZ8US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50042873(5'-(4-Ethoxy-phenylcarbamoyl)-[2,2']bipyridinyl-5-...)copy SMILEScopy InChI
Affinity DataIC50: 320nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105223(US8580778, 26)copy SMILEScopy InChI
Affinity DataIC50: 380nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3543(US8524699, 16)copy SMILEScopy InChI
Affinity DataIC50: 480nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105217(US8580778, 5)copy SMILEScopy InChI
Affinity DataIC50: 540nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3555(US8524699, 3)copy SMILEScopy InChI
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105218(US8580778, 9)copy SMILEScopy InChI
Affinity DataIC50: 760nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM105216(US8580778, 2)copy SMILEScopy InChI
Affinity DataIC50: 880nMAssay Description:In vitro tests for determination of the activity and selectivity of HIF prolyl 4-hydroxylase inhibitors. Hydroxylated HIF bonds specifically to the ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q21C1VH5US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3591(US8524699, 7)copy SMILEScopy InChI
Affinity DataIC50: 880nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3623(US8524699, 28)copy SMILEScopy InChI
Affinity DataIC50: 890nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM109271(US8609698, 65)copy SMILEScopy InChI
Affinity DataIC50: 900nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44NZ8US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM109269(US8609698, 18)copy SMILEScopy InChI
Affinity DataIC50: 910nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44NZ8US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3629(US8524699, 46)copy SMILEScopy InChI
Affinity DataIC50: 930nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50368560(CHEMBL1744254)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50000409(5-Benzenesulfonylaminocarbonyl-pyridine-2-carboxyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3643(US8524699, 44)copy SMILEScopy InChI
Affinity DataIC50: 1.12E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50368564(CHEMBL1203805)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM109272(US8609698, 80)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44NZ8US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3644(US8524699, 55)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50368562(CHEMBL1744252)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50368565(CHEMBL1203806)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50368561(CHEMBL1744251)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3698(US8524699, 22)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3723(US8524699, 6)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50000400(5-Phenylmethanesulfonylaminocarbonyl-pyridine-2-ca...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM109270(US8609698, 22)copy SMILEScopy InChI
Affinity DataIC50: 3.24E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44NZ8US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM109273(US8609698, 89)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44NZ8US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM3734(US8524699, 26)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+3nMpH: 7.5 T: 2°CAssay Description:In Vitro assay determination of the activity and selectivity of HIF Prolyl 4-hydroxylase inhibitors.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB15J4US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50000438(5-(4-Dimethylamino-phenylcarbamoyl)-pyridine-2-car...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50000416(5-(Naphthalene-1-sulfonylaminocarbonyl)-pyridine-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50000430(5-(4-Ethoxy-phenylcarbamoyl)-pyridine-2-carboxylic...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM50042872(3-phenylsulfonamidocarbonyl-6-(5-phenylsulfonamido...)copy SMILEScopy InChI
Affinity DataIC50: 5.04E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.18E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase by chromatographic determination of [14C]-succinic acid on ion-exchange minicolumnaMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RJ4HJVPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM109267(US8609698, 8)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G44NZ8US Patent
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of prolyl 4-hydroxylaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3M3CPubMed
TargetTransmembrane prolyl 4-hydroxylase(Homo sapiens (Human))TBA
LigandPNGBDBM26114(CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of prolyl 4-hydroxylase activity by an indirect assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3R9DPubMed
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